The University of Chicago
Ancient DNA Lab
The Ancient DNA (aDNA) lab at the University of Chicago is one of just a small number around the world and HERA was asked to program and plan a state-of-the-art lab that will enable world-class research by the Human Genetics Department.
This showcase lab is used to help recruit and retain researchers and students who will be recovering DNA from the far past from mummified tissue, skeletons or hair samples to study the genome of modern-day populations of humans.
The aDNA lab is a 24/7 operation that requires tight security and exacting power, temperature and cleanliness levels to perform at optimum efficiency.
The lab is composed of three separate areas of a minimum of ISO 7 cleanroom:
- The antechamber for storage, receiving, gowning and general entrance
- The sample prep room for dirty work, including grinding, drilling and extracting
- The wet lab for DNA library prep houses an ISO 5 biosafety cabinet
Based on the space requirements HERA developed, The University of Chicago selected two locations on campus. HERA collaborated with the university to evaluate those options and develop a design and construction budget for each.
The final location, in the Gordon Center for Integrative Science, was selected in part because it allowed the lab to be purposely separated from other genetic labs to avoid contaminating the samples with modern DNA.
1,643 gross square feet
Program validation and space selection/planning